Defender Jean-Clair Todibo received the quickest red card in Ligue 1 history by getting sent off just nine seconds into Nice’s home defeat by Angers.
Ex-Barcelona centre-half Todibo was adjudged to be the last man for a trip and was immediately dismissed.
Former Tottenham midfielder Nabil Bentaleb scored the winner goal for Angers in the first half.
The visitors also finished with 10 men after ex-Southampton winger Sofiane Boufal received two yellow cards.
Englishman Ross Barkley appeared for the hosts in the second half, but Wales international Aaron Ramsey missed out through injury.