Chris Smalling headed a 78th-minute winner as Roma came from behind to beat Inter Milan at the San Siro and jump to fourth in the Serie A table.
Smalling rose highest to nod in Lorenzo Pellegrini’s free-kick and ensure Roma beat their rivals for the first time since February 2017.
Federico Dimarco had opened the scoring for Inter after 30 minutes.
But the visitors were level nine minutes later through Paulo Dybala’s volley from an acute angle.
Roma’s win saw them go to within four points of leaders Napoli, while Inter remain in seventh, eight points off the top having lost four of their eight Serie A matches so far this season.
Inter had had the better of the game’s chances overall. Hakan Çalhanoglu hit the bar from a free-kick in the 62nd minute.
Meanwhile former Roma striker Eden Dzeko had thought he had opened the scoring in the 11th minute only for his strike to be ruled out by VAR.