Neymar was taken off on a stretcher after going over on his ankle during Paris Saint Germain’s 3-0 win over Marseille on Sunday night.
TheBrazil star went down in agony and held his hands over his face as he was carried off of the pitch in the 80th minute.
PSG host Real Madrid in the return leg of their last-16 Champions League tie on March 6. They lost the opening encounter 3-1.
Shortly after the final whistle, PSG captain Thiago Silva told Canal+: ‘We lost a very important player before the end in Neymar and his ankle had already started to swell. I’m not a doctor but I don’t think he’ll be ready for Wednesday (in the French Cup quarter-final against Marseille).’
Manager Unai Emery was hopeful on Neymar’s condition.
He told the club’s official website after the 3-0 win: ‘The injury to Neymar was the only negative. We hope it is nothing serious, but we will wait for the scans.’
It had otherwise been an excellent night for Emery’s side. Kylian Mbappe, with his 10th league goal of the season, and a Rolando own goal put the Parisians in control before the break, and a superb Edinson Cavani strike rammed home the Ligue 1 leaders’ superiority.
PSG’s 23rd league win, from 27 games, extended their advantage at the top to 14 points after second-placed Monaco had drawn 3-3 at Toulouse on Saturday.
Marseille remain in third place, two points adrift of Monaco and with a five-point cushion over Lyon in the race for Champions League qualification.
PSG were in command from the 10th minute when Jordan Amavi failed to cut out Dani Alves’ pass.
Mbappe picked up the loose ball and stepped inside on his left foot to fire past defender Rolando and Yohann Pele in the Marseille goal.
Alves was again the provider with a cross Neymar narrowly headed wide, before the full-back was temporarily slowed by a poor Lucas Ocampos challenge.
The Argentine was booked for connecting with Alves’ shin, but he could easily have seen red for endangering an opponent.
PSG doubled their lead after 27 minutes when Layvin Kurzawa slipped in Adrien Rabiot down the left. Rabiot pulled the ball back into Neymar’s path and his shot diverted in off the luckless Rolando.
Neymar – who was sent off in the reverse fixture at Marseille in October – was almost on the scoresheet 10 minutes later but his attempt from 25 yards curled just wide.
Marseille did not muster any threat until the final moments of the first half, but even then Andre-Frank Zambo Anguissa’s header was comfortably collected by Alphonse Areola.
The contest was put well beyond them 10 minutes into the second half when Neymar’s power and pace took him past several defenders down the left.